If you have an interest in human biology, then in taking this course, you will gain an insight into a bio-physical model that maps evolution of the human circulation and that you can use for your own further observation and discovery
This course addresses evolution of the clrculation from fish to man through the physics of the redoxing blood circuit.
There are 21 lectures, split into four sections. Each lecture is only a few minutes long, the entire course less than 60 minutes. It can be taken in one sitting or at your own pace.
In the course, animated and physical models are used to demonstrate key mechanisms in the translation of form and these can be easily reproduced after the course if desired
In the first section, the circulations of blood in humans and fish are represented as double and single-looped polar-switching electron delivery circuits
In section two, we see how an oxygenated shunt in the single-looped circuit of fish sets up a loop-in-loop, reptilian transition to a double-looped human circuit
In section three, a polar co-ordinate algorithm that describes the loop-in-loop relationship of the adaptive, closed circulation model is described
In the final section, we review how this geometric model tracks embryological, anatomical and evolutionary form, from fish to man, and what drives the change.
There are some details in the latter part of the course for those with knowledge of human embryology and anatomy. This level of knowledge is not a pre-requisite for taking this course or understanding its general content, but it does serve to validate the bio-physical model.
Introduction to the circulation of blood in vertebrates as a closed one-way redoxing circuit
The human blood circuit is represented by a double-looped continuous tube. Unique physical properties relating to the convoulted, spatially complex redoxing circuit are highlighted through a model demonstration.
The fish blood circuit is represented by a single-looped continuous tube and comparisons are made to the redoxing, double-looped circuit
In this lecture, we will see how the continuously flowing, polar-switching blood creates opposed magnetic moments in the single and double-looped circuitries
Review the theory of evolution, from fish to man and question how a double-looped circuit can arise from a single looped circuit
We start with the single-looped circuit, identifying how a shunt can exist and the path it takes
The establishment of a pulmonary passage is key in the transition to a double-looped human circuit. This lecture establishes the mechanism of translation of the pharyngeal capillary bed from gill filaments to alveoli as the double-looped circuit develops.
In this lecture, the conceptual single-looped, axially rotated circuit is translated to the structural anatomy of the fish circulation.
Relating the loop-in-loop to extant anatomic arrangements, we see how an anatomic shunt arises and how the transitionary polar-switching circuit maintains a homeostatic balance in the geomagnetic field.
The loop-in-loop spatial relationship of the transformative circuit is best understood by first developing a physical model to capture its pivoting and precessing actions
In this lecture we define a polar co-ordinate algorithm that describes the spatial relationship of the interdependent central loops in translation
We start with the loop-in-loop dynamics in the pharyngeal arches and expose the mystery of the disappearing 5th arch...
In polar translation, as the central loops pivot toward perpendicular parity, the aortic arch and great vessels are derived.
This lecture highlights how the pulmonary passage develops in polar co-ordination with the involuting pharyngeal filaments.
The separate atrio-ventricular trajectories of the double-looped human heart are derived geometrically from the single-looped fish heart and the balance of flows between the serialiised loops is considered
In this lecture, we equate spiralled dynamic flows into the dorsal aorta with maintaining a bi-segmental somatomeric perfusion pattern and use the clinical condition of dextrocardia as a case-in-point
In the geometrical transformation we see how the dorsaly-located cardinal veins are levered apart and re-purposed as the spiralled aortic line develops
In this lecture we will see how the atrio-ventricular angle is retained in translation from a single to a double-looped-circuit and also ponder why the angle of ejection is this sharp reflection on itself.
Here we put the entire sequence together, tracing the transition from fish to human, through our blood, and see how the allantoic vein is an accelerated source of the oxygenated loop-in-loop shunt in gastrulation
The loop-in-loop is an oxygen-driven system and here we review animal evolution against environmental oxygen levels the past 500 million years
As an observation, the polar-switching haem electron-carrier circuit mirrors vertebrate evolutionary progression and cardio-morpho-genesis.
Dr Peters has a Doctorate of Medicine (Monash) and over 25 years of clinical experience and preclinical research, covering surgical correction of congenital and acquired heart disease, heart and lung transplantation and mechanical cardiac assist device surgery. He is currently an honorary senior lecturer in surgery at Auckland University, NZ. Dr Peters was the inaugural clinical research fellow in minimally-invasive cardiac surgery at Stanford University (1994-95). and has many published manuscripts and issued patents regarding key-hole heart surgical devices and methods as well as regarding an implantable, bloodless mechanical circulatory support device. Dr Peters has mentored surgeons through related first-in-man surgeries in the USA, Canada, Germany, England, Australia and NZ. He published his first book, 'Per Sanguinem Nostrum', on the circulation of blood, in 2015. Research interests include the physics of the redoxing blood circuit and its relationship to vertebrate growth and form.