Learn Bioinformatics in 6 Days
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Learn Bioinformatics in 6 Days

Kickstart Your Journey to be a Bioinformatician!
3.8 (8 ratings)
Instead of using a simple lifetime average, Udemy calculates a course's star rating by considering a number of different factors such as the number of ratings, the age of ratings, and the likelihood of fraudulent ratings.
55 students enrolled
Created by Isaac Alfred
Last updated 6/2017
English
Curiosity Sale
Current price: $10 Original price: $35 Discount: 71% off
30-Day Money-Back Guarantee
Includes:
  • 4.5 hours on-demand video
  • 2 Articles
  • 28 Supplemental Resources
  • Full lifetime access
  • Access on mobile and TV
  • Assignments
  • Certificate of Completion
What Will I Learn?
  • Integrate biological concepts with information technologies to study the biological system.
  • Apply the theoretical and computational methodologies relevant to the mining of information from large datasets of biological origin.
  • Combine theory and practice to solve research problems in bioinformatics, genomics and proteomics.
  • Manipulate data on computer and understand of the algorithms that underlie the analysis tools that are used for essential research tasks.
View Curriculum
Requirements
  • An interest in learning Bioinformatics and maintaining the same interest constantly throughout the period of study.
  • A knowledge in molecular biology, basic genetics and other life science related courses would be an advantage but not necessary.
  • Some chapters require you to donwload and install certain softwares for the analysis tutorial. You need to have at least a personal laptop or a desktop with a minimum 4GiB RAM and enough storage capasity for data storing.
  • Good qualitative (semantic) and quantitative (mathemathics/statistics) reasoning.
Description

When the current deal is above USD10, kindly use this promotional code to get a flat price at USD10 instead. The code is ALFRED12 (valid through 1st July to 31st August 2017).


It's WORTH your money! This program runs through 6 chapters. This is a self-paced course that suits to your own daily busy schedules. Self-paced gives you the freedom to complete each topic based on your own available time before proceeding to the next chapter without hurry. Basically, I will teach about 6 fundamental topics in Bioinformatics to you. Just to let you know, I don't intend to cover a basic programming class here. Udemy has a lot of great programming courses that can be applied in a Bioinformatics settings. So please well equip yourself with at least Python, Perl, PHP, Java, SQL and R programming. That will really help you to take off faster as a Bioinformatician in the near future. In 6 days you will learn through video lectures and tutorials about:


Day 1 - Introduction to Bioinformatics

  • We will start this course with a brief definition of Bioinformatics - what exactly it constitutes of, and the importance of this field in the scientific world. Also, I will share with you the history of how Bioinformatics came into being - the reason why it was coined.

Day 2 - Bioinformatics Databases

  • One of the reasons why Bioinformatics exists is due to the increased amount of biological datasets. These are huge scientific research outputs that need to be managed. In this chapter you will learn first of all how data is stored and manipulated. Subsequently I will begin to introduce to you about nucleotide databases. Bioinformatics is all about managing data and providing scientific knowledge. In this chapter we will also  focus on protein databases. These two types of databases compliment each other and both are important for your studies. An example of database that we will be covering here is UniProt.

Day 3 - Sequence Alignment

  • This is one of my favorite chapters. Have you ever wonder how two sequences are being compared using two different sequence alignment algorithms? Think about aligning 100 DNA sequences at one time - is there a way to perform the multiple sequence alignment? In this chapter I will teach you how to perform Global and Local sequence alignments - it's all about basic concepts of scoring matrices. Let's get serious with Bioinformatics from here onward!

Day 4 - BLAST programs

  • Yeaps! Also my favorite! I will teach you how to perform a Local sequence alignment using a Bioinformatics tool known as BLAST (Basic Local Alignment  Search Tool). We will look into both nucleotide and protein sequence BLAST programs and learn how to read and interpret BLAST results in-details.

Day 5 - Molecular Phylogenetics

  • Let's get straight to the point. You are uniquely different and special! If you are a big fan of X-Men and other Sci-Fi Hollywood movies talking about aliens, superhuman, man with extraordinary powers, or even just about how diversified we are - this is the time to pay attention to this module. I will teach you about how species is identified and classified using genetic data. To do that we will also be looking into several types of phylogeny analysis algorithms and construct a tree of life from a specific set of sequences. Don't skip this session!

Day 6 - Genome Analysis

  • In this module you will learn about a genome. We will look closely into both structural and comparative genomics. The detail parts begin with the sequencing technologies and followed with genome assembly and annotation.



I have prepared several sets of quizzes and assignments for you to solve. Based on previous experiences with other students, I am aware that some of you might need a one-to-one discussion therefore you are welcome to request for an online meeting / discussion session with me. Just to help you progress in this course. By the way, the first chapter is F.O.C. for preview! Register now to start learning about what Bioinformatics can do to help you, be it in research routines or for career development or simply just for personal interest. You have a lifetime access to this course and the course materials will be updated periodically. Do check for updates from time to time.

Who is the target audience?
  • Anyone who wants to learn Bioinformatics.
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Curriculum For This Course
38 Lectures
04:31:11
+
Course Introduction & Content
4 Lectures 19:06

There are several things that you need to know before you start the course. In this lecture I will explain to you about the course structure and contents as well as the learning outcomes that you will gain from this course.

Preview 02:32

We will look into several phases of scientific development and growth until to the advent of Bioinformatics which accelerated the advancement of biotechnology research.

Preview 06:05

This is just a refresher topic for those who are familiar with the central dogma of molecular biology. For those of you are not from the biotechnology background, this could be something new.

Preview 07:04

Learning basic analysis will definitely help you to understand better in doing advanced Bioinformatics works. Here I will briefly explain about the current analysis trends in Bioinformatics.

Preview 03:25

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
19 questions
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Day 2 - Bioinformatics Databases
8 Lectures 01:17:13
Learning Objectives and Outcomes
00:48

In order to fully understand what database is, it is important to know the purpose and the structure of a database. Since it is a computer system that stores information, it is ideal to know why we need a database in scientific research.

Introduction to Database & File Format
09:10

Here in this section we will look specifically into GenBank and some other nucleotide databases. I will teach you on how to perform a query from GenBank.

Nucleotide Sequence Databases
07:28

Nucleotide databases are not the only type of databases you will learn. I will also introduce to you on the protein databases. pay a closer attention on this section as we will be covering a specific chapter on Proteomics alone later on.

Protein Databases
06:30

Guide - Browsing GenBank - Part 1
13:49

Guide - Browsing GenBank - Part 2
15:36

Guide - Browsing UniProt
12:31

Guide - Build a simple database using Microsoft Access
11:21

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
18 questions

Exploration of GenBank gene information.
Find the gene!
6 questions
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Day 3 - Sequence Alignment
7 Lectures 46:02
Learning Objectives and Outcomes
00:58

In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences.

Sequence Alignment
05:52

Let's try to align two nucleotide sequences together and observe how many types of alignment we can get and then decide which one is the best alignment. In this section, I will explain to you on just that alone.

Simple Alignment
05:33

Extra - Sequence Alignment
04:28

There are two methods to perform a sequence alignment - local and global sequence alignments. In this section you will learn how to construct both local and global sequence alignment matrices in order to understand how alignment algorithm works.

Scoring Matrix & Dynamic Programming Algorithm
09:29

Extra - Scoring Matrices
04:59

Guide - Multiple Sequence Alignment using ClustalX
14:43

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
13 questions

This is a pairwise sequence alignment assignment. You may use either NCBI BLAST or ClustalX for the analysis.
Investigating the correlation between human and rat genes.
4 questions
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Day 4 - BLAST programs
4 Lectures 30:27
Learning Objectives and Outcomes
00:50

In bioinformatics, BLAST for Basic Local Alignment Search Tool is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA sequences.

A BLAST search enables a researcher to compare a query sequence with a library or database of sequences, and identify library sequences that resemble the query sequence above a certain threshold. Different types of BLASTs are available according to the query sequences 

BLAST Programs
13:47

The BLAST algorithm and the computer program that implements it were developed by Stephen Altschul, Warren Gish, and David Lipman at the U.S. National Center for Biotechnology Information (NCBI), Webb Miller at the Pennsylvania State University, and Gene Myers at the University of Arizona.
BLAST on NCBI
06:13

Guide - How to perform a BLASTn search
09:37

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
17 questions

Use BLAST to discover SNP.
Find the mutation!
10 questions

Find the information related to a protein based on GenBank accession number.
Find the protein!
4 questions
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Day 5 - Molecular Phylogenetics
8 Lectures 50:40
Learning Objectives and Outcomes
01:18

Molecular Evolution
10:39

Understanding Evolution
08:47

Reading Phylogenetics Tree
07:53

Building Guide Tree
05:45

Which Method to Use
08:20

Quality Assessments
07:41

In this section, I have provided the installer for Mega version 6, a zipped folder containing the FASTA sequence file for Ruminants, and the User Manual on how to perform the phylogenetic tree construction using Mega 6. All you need to do is to follow through the User Manual. The download links are as below. If you have any question, do share with me through the comment box. Thank you.

Guide - Let's Build a Phylogenetic Tree
00:17

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
11 questions

Try to perform a phylogenetic tree using Mega 6.
Constructing a phylogenetic tree
1 question
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Day 6 - Genomics
7 Lectures 47:42
Learning Objectives and Outcomes
00:49

Introduction to Genomics
07:48

Sequencing Technologies Overview
15:08

Genome Assembly
09:38

Genome Annotation
06:53

Comparing Genomes
06:51

IMPORTANT!

Please be reminded that you are expected to do your own revision and finding extra information about anything that is in relation to each chapter.

Test your knowledge
16 questions

Online Tutorials on UGENE
00:35
About the Instructor
Isaac Alfred
3.8 Average rating
8 Reviews
55 Students
1 Course
ALFRED Initiatives

I am currently a part time Bioinformatics lecturer at local private university in Kuala Lumpur. At the same time I am managing my own startup in Bioinformatics. 

Previously, I was actively involved in the Bioinformatics industry. Having been in the industry since 2007, I have the call to share my knowledge and experiences to learners like you.

My teaching skills might not be as good as experienced instructors on Udemy who made handsome profits from their courses, but I am sure that I have a sincere passion to teach, to broaden my professional networks, and to make money for myself.

By the way, I encourage you to read "The $100 Startup" by Chris Guillebeau.

Cheers!

Alfred.