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Preclinical Basics: Toxicity, Bioimaging & Literature
Rating: 3.3 out of 5(2 ratings)
18 students

Preclinical Basics: Toxicity, Bioimaging & Literature

Preclinical research ,toxicity models, scientific literature search, science images, bioimaging, toxicity study.
Created byDr Pravin Badhe
Last updated 4/2023
English

What you'll learn

  • Describe the basic principles of preclinical toxicity assessment, including types of toxicity, routes of exposure, and dose-response relationships.
  • Explain the use of bioimaging techniques in preclinical research, including their advantages, limitations, and applications in toxicity assessment.
  • Conduct an effective literature search using a range of databases and search tools, and critically evaluate and synthesize information from scientific literatur
  • Understand the ethical and regulatory considerations in preclinical research, including the use of animal models and compliance with relevant regulations and gu
  • Analyze and interpret preclinical data, and effectively communicate findings to different audiences, including scientific experts and non-expert stakeholders.

Course content

5 sections • 30 lectures • 1h 43m total length

  • Introduction to literature search3:03
  • Process of Literature Search2:51
  • Defining a Research Question3:32
  • How to choose an appropriate source for literature search3:17
  • Use of keywords and search terms in literature search3:06
  • Evaluate the sources3:25
  • Read with purpose2:04
  • Peer reviewed publications2:47
  • Types of articles3:15
  • Impact factor2:57
  • Plagiarism6:56
  • Machine learning in article search3:36

Requirements

  • The prerequisites for this course may include a basic understanding of biology, chemistry, and/or related scientific fields. It may also be helpful for learners to have some familiarity with scientific terminology and research methods. Additionally, familiarity with basic computer skills such as using search engines and databases is recommended for the literature search component of the course. However, this course is designed to be accessible to a wide range of learners and does not require any advanced or specialized knowledge

Description

The development of new drugs is a complex and costly process, and the preclinical phase is a critical step in ensuring that new therapeutic candidates are safe and effective before they progress to clinical trials. This course aims to provide students with a comprehensive understanding of the essential preclinical concepts of literature, toxicity, and bioimaging.

In the literature component of the course, students will learn how to navigate the vast amount of preclinical literature available to researchers and scientists. They will be introduced to various databases, search engines, and analytical tools to extract relevant information and interpret findings. They will also learn how to critically evaluate preclinical literature and identify gaps in current knowledge.

The toxicity component of the course will introduce students to the fundamental principles of preclinical toxicology and safety assessments. They will learn about different types of toxicity models and how to interpret toxicity data. Students will also gain an understanding of the regulatory requirements for preclinical safety testing, including the use of animal models.

In the bioimaging component of the course, students will learn about the various imaging techniques used in preclinical research. They will be introduced to different imaging modalities, such as magnetic resonance imaging (MRI), positron emission tomography (PET), and computed tomography (CT), and learn how to choose the appropriate imaging modality for different preclinical applications. They will also learn how to interpret imaging data and integrate it with other preclinical data.

At the end of the course, students will have a comprehensive understanding of preclinical literature, toxicity testing, and bioimaging and be equipped with the necessary skills to apply these concepts in their own research.

Who this course is for:

  • This course is designed for individuals who are interested in pursuing a career or further studies in preclinical research, including toxicology, pharmacology, and drug development. It may also be of interest to researchers, scientists, and healthcare professionals who want to gain a better understanding of preclinical research and its applications. This course is suitable for learners with diverse educational and professional backgrounds, including students, early-career professionals, and seasoned researchers.

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