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Nanotechnology Part 2: Micro-Fluidics, Droplets and Capsules
Rating: 3.8 out of 5(16 ratings)
164 students

Nanotechnology Part 2: Micro-Fluidics, Droplets and Capsules

understanding of fluidis behavior at the microscale, applications of micro- drops and capsules
Last updated 12/2022
English

What you'll learn

  • Behavior and properties of fluids at the microscale
  • Fabrication of glass capillary and PDMS microfluidic devices
  • Mechanisms of micro- capsules and drops formation
  • Life at Low Reynolds Numbers
  • Navier-Stokes equations
  • Weber, Reynolds and Capillary numbers
  • Surface charges and the electrical double layer
  • Electrosmosis, streaming potential
  • Electrokinetic phenomena
  • Pressure-, gravity-, electroosmosis-driven flows
  • The concept of a continuum
  • Microswimmers that utilize and overcome Brownian diffusion
  • Fluids mixing by stirring and diffusion
  • Example of application: electroosmotic pumping

Course content

3 sections5 lectures40m total length
  • Intro7:12

Requirements

  • Threre is no specific requirements

Description

Nanoscale fluidics or microfluidics studies the behavior of fluids at the microscale. The properties of fluids become fundamentally different. For example, at very low Reynolds, number water in tiny channels becomes as viscous as honey (without a change of viscosity, only by reducing the dimensions). The fluid-liquid interface is charged, where molecules accumulate. It is challenging to pump fluids through microchannels using mechanical pressure. It turned out that applying small currents requires much less energy or electroosmosis. It also affects tiny swimmers like bacteria or microrobots, which cannot utilize the motion strategy of big creatures. Biological cells are very different from the mechanical design of other man-made machines. Cells are microfluidic containers with rapidly mixing and reacting molecules that meet several times per second due to ultra-short traffic and diffusion time. During past decades new microfluidic devices have been discovered that utilize properties of fluids at a small scale. For example, glass capillary and PDMS microfluidics are used to manipulate fluids at a low Reynolds number to fabricate droplets and double emulsions. These products have multiple applications in the design of new ultra-light materials with new properties, agriculture, cosmetics, medicine, and environmental science. For example, using picoliter drops, high-throughput screening on the target of interest helps conduct thousands of experiments per second using minimal reagents. It enables the screening of millions of reactions, such as during the discovery of new drugs, in a short time. The course contains back-of-the-envelope calculations and multiple examples for students and scientists interested in experimental droplet microfluidics.

Who this course is for:

  • Students, engineers and scientists working in experimental science