Mathematically Modeling Enzyme Kinetics

Name: Mathematically Modeling Enzyme Kinetics
Rating: 4.3 (30 reviews)

Learn to mathematically model enzyme kinetics.

Created byASIJ iGEM, Stephanie Eristoff

Last updated 9/2019

English

What you'll learn

Enzyme Kinetics
Differential Equations
Law of Mass Action
Equilibrium
Synthetic Biology

Course content

4 sections • 15 lectures • 1h 20m total length

Introduction0:28
Requirements and Prerequisites0:34

Background of Henri-Michaelis-Menten Kinetics2:01
Explore the background of Michaelis-Menten kinetics, linking qualitative enzyme reactions, inhibition types, and graphs to quantitative models of product formation using substrate affinity and forward/reverse rates.
Graph Components4:31
Derivation of Henri-Michaelis-Menten Kinetic Law9:14
Derivation of Competitive Inhibition Kinetic Law13:41
Derive the competitive inhibition kinetic law using mass action and rapid equilibrium, expressing the rate as v = Vmax[S]/([S] + Km(1 + [I]/Ki)).
Derivation of Uncompetitive Inhibition Kinetic Law9:53
Kinetic Law Review

Requirements

Calculus I (AP Calculus AB)
Basic Chemistry (Stoichiometry)

Description

Learn how to mathematically model enzyme kinetics!

In this course, students will learn to fully understand the background of enzyme kinetics, the concept of equilibrium and the law of mass action, the mathematics behind enzyme kinetics.

We hope that you enjoy this course and will find the skills useful for iGEM and beyond.

Who this course is for:

iGEM Students
Highschool Students

Mathematically Modeling Enzyme Kinetics

What you'll learn

Explore related topics

Course content

Introduction2 lectures • 1min

Introduction to Enzymes6 lectures • 27min

Equilibrium and the Law of Mass Action2 lectures • 13min

Math Behind Enzyme Kinetics5 lectures • 39min

Requirements

Description

Who this course is for: