
Learn how laboratory billing uses the order to cash cycle to secure payment from Medicare, Medicaid, and private payers through CPT and ICD coding, NPI, and Clea certification.
Explore clinical, pathology, and genetic testing types, and learn how each affects billing and coding through documentation, professional and technical components, and precise CPT/ICD coding.
Explore the differences between professional and facility billing, including revenue codes, place of service, the tc and pc components, modifier 26 and modifier tc, and payer policy impacts on reimbursement.
Understand how in-house and reference laboratories bill for tests, from ownership and location to who bills the payer, and how CLIA numbers and modifier 90 indicate where testing occurs.
Learn how laboratory billing differs from hospital and physician billing, using CMS 1500 vs UB-04 forms, and how place of service, revenue codes, and global versus split billing affect reimbursement.
Learn how Medicare parts A and B cover inpatient and outpatient lab testing, compare traditional Medicare with Advantage plans, and apply NCD, LCD, and accurate coding rules for reimbursement.
Navigate commercial insurance plans—HMOs, PPOs, EPOs, and ASO arrangements—and learn how in-network contracts, prior authorizations, medical policies, and coordination of benefits shape laboratory billing and reimbursement.
Physicians must sign lab orders and include an NPI to confirm medical necessity. Facilities must include CLEA and NPI, document results, and retain records for audits and compliance.
Clarify the responsibilities of ordering providers and performing providers in laboratory billing. Ensure accurate NPIs, proper documentation, medical necessity, and clear role separation to avoid denials.
Explore how laboratory technicians and pathologists collaborate to ensure accurate documentation, chain of custody, and quality control, enabling compliant billing with TC/PC components, 26 modifiers, SOPs, and CLIA.
Understand Clea CLIA certification levels—waived, moderate, and high complexity—and how they determine tests and CPT codes billed, using the QW modifier and site-specific Clea numbers to prevent denials.
Learn the essential components of a valid lab order: patient identifiers, provider NPI and signature, tests linked to ICD-10 codes, and specimen type with collection date and time.
Master how diagnosis linking connects laboratory tests to medical necessity, ensuring compliant and reimbursable billing by aligning ICD-10 codes with CPT/HCPCS services.
Master medical necessity, coverage determinations, and payer guidelines to ensure laboratory reimbursement under NCDs and LCDs, with ABNs and prior authorization guiding when tests are paid.
Master HCPCS level II codes for lab services and supplies, including G codes, P codes, 36415 venipuncture, Clea certification alignment, and kit billing under payer rules for compliant Medicare reimbursement.
Learn laboratory billing modifiers: 90 for outsourced reference labs, 91 for medically necessary repeats, QW for CLIA waived tests, and 59/X for distinct services.
Link lab tests to diagnosis codes with ICD ten to show medical necessity and secure reimbursement. Identify primary versus incidental findings and apply z or symptom codes based on intent.
Prevent medical necessity denials by using edit checks and updated crosswalks, and protect revenue with abn and standardized appeal templates supported by clinical documentation.
Apply Medicare rules for lab services by enforcing reasonable and necessary standards, distinguishing covered versus non-covered, using NCDs and LCDs, checking eligibility and MBI, noting frequency limits, and issuing ABNs.
NCDs and LCDs shape Medicare lab coverage by providing national and regional rules, code lists, and documentation requirements; labs must use ABNs to manage potential nonpayment and reduce denials.
Learn how Medicare enforces frequency limits, muas, and NCCI edits, and how labs prevent and appeal automatic denials. Verify prior test history and document medical necessity to reduce denials.
Explore how labs navigate major commercial contracts with UHC, Aetna, Cigna, and BCBS, including fee schedules, payer portals, carve outs, prior authorization, denials, and escalation for payment accuracy.
In-network lab billing streamlines authorizations and predictable patient costs through payer contracts. Out-of-network billing entails stricter approvals, possible balance billing, and No Surprises Act considerations.
Identify commercial payer denials for labs, including medical necessity mismatches, missing prior authorizations, duplicate or investigational services, and COB or out-of-network issues; verify ICD-10 linkage and eligibility to speed payments.
Learn to navigate lab claim denials through timely appeals and reconsideration, assembling strong evidence, standardized templates, and tracking to drive revenue recovery and ongoing compliance.
Master Ub04 Cms 1450 for facility-based lab billing and align revenue codes with cpt/hcpcs. Complete tobe, occurrence, and value codes and ensure physician npis are correct to avoid denials.
Compare electronic data interchange (EDI) billing with paper claims for labs, explain clearinghouse validation, attachments, and when payers require paper submissions to reduce denials.
Learn how pathology specimens are billed with tc and 26 modifiers for technical and professional components using 883 codes, and ensure split vs global billing with block and slide documentation.
Learn to code molecular and genetic tests with tier one, tier two, and PLA codes, apply Mold DX requirements and Z codes, and secure prior authorization for compliant reimbursement.
If you want practical, job-ready skills in medical billing, medical coding, revenue cycle management (RCM), A/R calling, payment posting, prior authorization, Medicare, HIPAA, health data, EHR, and US healthcare—this laboratory-focused course is for you.
This course is designed to help learners of all backgrounds understand and apply laboratory medical billing and revenue cycle management in real-world healthcare settings. Whether you’re working in medical coding, billing, administration, or healthcare IT, this course builds a strong foundation in the lab billing workflow—from orders and requisitions to coding, claim submission, payment posting, and denial prevention.
You’ll learn how CPT/HCPCS and ICD-10-CM interact to support medical necessity, how payer rules (especially Medicare) shape coverage, and how to operationalize HIPAA-compliant processes across EHR and clearinghouse environments. The curriculum follows your course sections step-by-step: lab orders, coding, forms, payer-specific scenarios, audits, fraud prevention, technology, and “getting hired” pathways for laboratory billers.
Designed to be beginner-friendly, the course includes clear explanations, downloadable templates, checklists, and realistic examples from EHRs, ERAs/EOBs, and lab billing documentation to reinforce learning. No prior experience is required.
What You’ll Learn
Map the full laboratory RCM lifecycle from order to zero balance
Apply CPT/HCPCS and ICD-10-CM to common lab services and diagnoses
Build clean claims (CMS-1500/837P) and reduce rejections/denials
Manage prior authorizations, eligibility, and benefits verification
Post payments accurately; reconcile ERAs/EOBs and handle takebacks
Navigate Medicare rules, NCDs/LCDs, ABNs, and payer edits
Use dashboards to track A/R aging, first-pass yield, and KPIs
Operate within HIPAA, fraud/waste/abuse, and audit-ready controls
Course Features
70+ bite-size videos aligned to the lab billing workflow
Realistic case files: test panels, reflex testing, repeats, add-ons
Clean-claim checklists, medical-necessity tools, and denial playbooks
Medicare policy walk-throughs (NCD/LCD), ABN examples, payer specifics
Hands-on templates for A/R follow-up, payment posting, and appeals
Technology module: clearinghouses, EHR interfaces, edits, and rules engines
Career module: resume tips, interview questions, and starter portfolio
Who This Course Is For
Aspiring and current medical billers, coders, and lab RCM staff
AR callers, payment posters, and denial/appeals specialists
Prior-auth teams, front office staff, and benefits coordinators
Lab managers, practice owners, and healthcare administrators
EHR/healthcare IT analysts supporting billing and claims
Students entering US healthcare who want a lab billing niche
Disclosure: This course contains the use of artificial intelligence for clear voiceovers.