
Learn to read and interpret scientific papers by navigating the structure, methods, and results, and master concepts like randomized trials, study types, statistics, diagnostic testing, adverse events, and impact factors.
Understand the structure of a scientific paper, from the title and authors to the abstract, introduction, methods, results, discussion, and conclusion. Note funding disclosures to gauge potential biases.
Identify reliable information sources for medical topics, such as the American Heart Association, MedlinePlus, PubMed, and Google Scholar, to understand terms like hypertension and left ventricular hypertrophy.
Tailor your reading of a scientific paper to your goal, whether you are a medical writer, researcher, or the public, by focusing on abstract, methods, results, and discussion.
Meta-analysis combines data from multiple studies to yield a more powerful, statistically significant conclusion, as seen in atrial fibrillation where newer blood thinners reduce stroke risk versus warfarin.
Understand the evidence hierarchy of study types, from case reports bottom to large randomized controlled trials, systematic reviews, and meta-analyses top, noting how randomized trials reduce confounding and recall bias.
Here's a cheat sheet listing the main outcome measures that you may need to know.
A little more information about confidence intervals and P values, plus a couple of examples.
Explore how diagnostic tests assess disease status by measuring sensitivity and specificity, and distinguish true positives, true negatives, false positives (type 1 error), and false negatives (type 2 error).
Assess adverse events and their rates, including placebo use, to understand outcomes. Compare active versus placebo controls, note blinding, and consider peer review and impact factor shaping findings.
Evaluating the addition of Brentuximab to ABVD for Hodgkin's lymphoma, the study shows a 2-year modified progression-free survival of 82.1% versus 77.2% (HR 0.77, p=0.03).
Get your head around the scientific literature! If you are a grad student, patient, medical student, clinician or researcher who needs to be able get their head around a scientific paper, then this course is for you. It’s my belief that you don’t need an extensive scientific background in order to be able to understand and make sense of a scientific paper. This course, in a straightforward way, will get you up and running in no time and help you form your own opinions about the science.
Perhaps you do have a background in science. If that’s the case, you will still get a lot out of this course and build on the skills that you already have.
Save precious time! An important approach to reading a scientific paper is to determine up front what you hope to get from the paper and avoiding having to sit there and read the whole thing. In this course, I will highlight the sections that will be helpful to read depending on your reason for reading the paper.
What makes me qualified to teach you? I’m Dr. Emma Nichols. I have a PhD in molecular biology and a Master’s degree in technical communication. After deciding that the lab and academia weren’t for me, I transitioned into medical writing. I’ve read many scientific papers in my time, and I’ve often had to digest papers quickly to meet deadlines as a medical writer and journalist. As a result, I’ve picked up a few shortcuts along the way!
I’ve been privileged to help a few folks start their career in medical writing through my 6-week course. Here are a couple of reviews:
“Emma’s enthusiasm is contagious and she has an obvious passion for helping people starting out in the medical writing business.” Gill S.
“The direct, personalized, insightful mentoring I received from Emma during and after the course is indispensable as I navigate the field of medical writing. I highly recommend Emma’s course to anyone serious about transitioning into medical writing.” Kelly C
This course will cover exactly what you need to know to read and interpret a scientific paper, including the following:
The structure of a scientific article
Important terms related to study population and trial design
Different study designs and their implications
Terms used to describe results
Statistical significance and confidence intervals
Sensitivity and specificity
Adverse events and placebo effect
Impact factor and peer review
At the end, I will discuss three papers and talk about how to approach reading them from the perspective of a patient, a clinician, and researcher, respectively.
What are the requirements? Most sections are suitable for people without a strong science background, but there is one section that goes into detail about different ways to report results and might be a bit slow going for someone who is not familiar with the topic. Likewise, some sections may be considered a bit rudimentary for people with a PhD or an MD, but it never hurts to brush up on your knowledge. In general, this course should appeal to anyone who has an interest of need to read the scientific literature.
My promise to you I am here on this planet to teach and communicate (especially about science and medicine). If you have any questions about the course content or anything related to this topic, you can always post a question in the course or send me a direct message.
Go ahead and click the enroll button, and I'll see you in lesson 1
All the best, Emma