
A brief note to say that you should not consider HEARThrive to be medical advice and that you should consult with your doctor or other medical professional regarding your health issues and concerns.
This course is actually a supplement to HEARThrive Module 1. It explains advanced blood testing that you can obtain to help assess your cardiometabolic health.
Module 1A contains some supplementary material about advanced testing for heart disease. Dr. Philip Ovadia is a heart surgeon that operates on patients (like me and my twin) who need bypass surgery. He certainly recognizes that we need delve in deeper and look beyond cholesterol and statin drugs to help predict our risk of cardiovascular disease.
No one can really say for sure what caused your heart disease or how you're going to fix it. Looking into advanced blood testing could produce answers.
In the next 4 videos Malcolm and Myron's advanced cardiometabolic testing done by SpectraCell will be described in detail. In this first video, we illustrate our Pre-diabetes risk factors. Fasting insulin, a key test, which doctors rarely request, is included in this panel. Pre-diabetes, often unrecognized due to poor testing, is a major condition that correlates to heart disease risk. You'll see 6 tests here and learn what each test means and the optimal reference range for each test.
This video also appears in HEARThrive Module 1 but It is included here again as it provides continuity in this discussion. Although a basic lipid panel is not particularly predictive for risk of heart disease, it does include measurements of triglycerides and HDL that are worth looking at closely. A doctor might say Myron, who takes a statin drug, is better off because he has lower cholesterol than Malcolm. But triglycerides and HDL paint a different picture, as demonstrated in this video.
Most health experts agree that a component of heart disease is chronic inflammation in the body. That's why SpectraCell includes vascular inflammation biomarkers in their cardiometabolic panel. Most of these are described in Module 1 of HEARThrive and in this video you will see how the values compare between me and my twin.
SpectraCell provides an advanced assessment of cholesterol. Cholesterol is transported inside lipoprotein particles in your bloodstream. Measuring and understanding these particle values is important. Malcolm does not take a statin drug (to lower cholesterol) but his twin brother does. Although some of Myron's advanced lipid values appear to be better controlled, there are some surprising differences in the twin's lipoprotein particle numbers. Several dietary and lifestyle suggestions are given that can improve poor lipoprotein profiles.
After Malcolm transitioned to a very low carb, animal-based diet in 2018, his cholesterol values (especially total cholesterol and LDL) skyrocketed upwards. Dave Feldman has studied this phenomenon and has tracked hundreds of people who, like Malcolm, follow this pattern. Malcolm's twin brother has not changed his diet and therefore his cholesterol values remain at levels that most people would call "good." Despite the now huge increase in Malcolm's total cholesterol and LDL values (July 2019), you will be surprised, maybe shocked to see which twin has the healthier lipid profile based on 3 different studies illustrated in this video. It comes down to having optimal triglyceride and HDL values (NOT LOW CHOLESTEROL).
Diet is a controversial topic but there are some important factors to learn in the next module that illustrate how diet impacts heart disease.
If there were a way you could predict whether you might be on the path toward heart disease you probably would want to know how to discover it. This is especially true if you learned this could be accomplished via simple blood tests. And it's even more encouraging when you realize there are simple things you can do starting now to help mitigate your future risks. Most doctors and cardiologists will look at your cholesterol and if it's high they will warn you about heart disease or a potential heart attack or stroke. It's easy to lower cholesterol using a statin drug, so that's what you'll be told to do. Unfortunately, you are receiving incomplete or possibly ineffective advice when they focus on cholesterol. You need to know a lot more about other factors that are even more important in predicting your cardiovascular risk. That's where advanced blood work comes in. You need a full cardiometabolic panel of tests to truly gauge your health. In Module 1A of HEARThrive you will learn about these tests. Malcolm and Myron Achtman both did the full SpectraCell cardiometabolic suite of tests in 2014, on the same day and at the same time. Each test will be explained in depth in this module. We now know the biggest risk factor associated with heart disease is diabetes. That's why SpectraCell begins with a Prediabetes panel that includes measurements of fasting glucose and hemoglobin A1c. Maybe you've had those tests, but has your doctor ever ordered other critical tests including fasting insulin, C-peptide and Adiponectin? SpectraCell includes these in their advanced testing. They also include a basic lipid panel, but we're going to focus much more closely on two measurements here that your doctor probably ignores - triglycerides and HDL. Next comes vascular inflammation markers. It's known that heart disease is integrated with chronic inflammation. The advanced array of SpectraCell's inflammation tests includes high-sensitive C-reactive protein, homocysteine, and Lp(a). These tests were discussed in Module 1 of HEARThrive as well. The gem among the tests is the advanced lipoprotein panel. Here we go way beyond routine cholesterol measurements and instead look in detail at the nature of lipoprotein particles that transport cholesterol in your body. These are believed to be a lot more predictive of heart disease risk and indirectly reflect your metabolic health as well.