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Fundamentals of Transmission Genetics/Classical Genetics

Name: Fundamentals of Transmission Genetics/Classical Genetics
Rating: 4.4 (28 reviews)

Mendelian Genetics, DNA as genetic material, Classical Genetics Experiment, Punnett Squares, Multiple Alleles, Mutations

Created byDr. Ibrar Khan

Last updated 8/2026

English

English [Auto],

What you'll learn

Define and understand Genetics and its historical Perspective
The classical experiments that proved DNA as the genetic material like Mendel laws, Griffith Experiment, Avery, Hershey and Chase and Morgan
A clear understanding of Punnett square, the Fork Line Method Dominance, co dominance, incomplete dominance
The structure of DNA and RNA and important regions of DNA, genes and alleles and the concept of multiple alleles
The Sex Linked Inheritance; X-linked Dominant and Recessive Traits
Mutations and Its Types along with their importance
Multiple Alleles, The ABO blood Types, Transfusions and Medical conditions

Course content

9 sections • 39 lectures • 9h 39m total length

Introduction to the Course2:21
This is just an introductory lecture and will give you an idea what we will be covering in this course
Definition and History of Genetics19:23
Applications of Genetics Part 19:00
This lecture will be a base for why to study Genetics and is focusing on some of the important applications of Genetics like selective breeding, preventing medicine and DNA paternity determination
Applications of Genetics Part 210:07
This lecture will be a base for why to study Genetics and is focusing on some of the important applications of Genetics like DNA fingerprinting, monoclonal antibodies and production of medicine (insulin)
Multiple Choice Questions

Classical Experiments, Thomas Hunt Morgan and Chromosomal Theory of Inheritance15:41
I usually discuss the experiments conducted in 19th century before going to Mendel laws because this highlights the greatness of Mendel and his laws. This lecture is focusing on the experiment of Thomas Hunt Morgan on fruit flies (Drosophila Melanogaster )
Classical Experiments; Griffith's Experiments on pneumococcus bacteria6:20
Griffith's experiments was a milestone and a backbone which ultimately lead to the discovery of DNA as the genetic material
Multiple Choice Questions
Classical Experiments; Avery–MacLeod–McCarty experiment5:19
The experiments of Avery–MacLeod–McCarty showed that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it was proteins that served the function of carrying genetic information
Multiple Choice Questions
Classical Experiments; Hershey-Chase experiment9:42
Hershey-Chase experiment was the final experiment, also called the Waring Blender experiment, through which Hershey and Chase showed that phages only injected their DNA into host bacteria, and that the DNA served as the replicating genetic element of phages
Multiple Choice Questions

Differences between DNA, Gene and Chromosome5:36
Explain how DNA, genes, and chromosomes differ: DNA serves as a long instruction manual; genes are small DNA sections; chromosomes pack DNA in the nucleus with histones.
Multiple Choice Questions
Structure of Nucleic Acids; DNA and RNA33:50
The genetic material in living cells is Deoxyribonucleic Acid OR Ribonucleic Acid. So it is very important to understand the structure of DNA and RNA and the differences between two; the focus of this lecture.
Quiz on the Structure of DNA/RNA
Why thymine is present in DNA and Uracil in RNA11:12
DNA uses thymine instead of uracil because thymine has greater resistance to photochemical mutation, making the genetic message more stable. Outside of the nucleus, thymine is quickly destroyed. Uracil is resistant to oxidation and is used in the RNA that must exist outside of the nucleus.
Multiple Choice Question "why thymine is present in DNA and Uracil in RNA"
Important regions in a DNA molecule9:29
Three important regions in a DNA molecule make it capable of producing the proteins, RNAs as well as a molecule of inheritance
Multiple Choice Questions on "Important regions in a DNA molecule"
Nucleoside and Deoxynucleoside3:55
Multiple Choice Questions

Mendel Laws; Part 1; Law of Dominance and Law of Segregation26:13
Gregor Johann Mendel, truly known as the father of Genetics, started experimenting on pea plant in the middle of 18th century. His wisdom and great experiments gave birth to the field of genetics. He was unaware of the details of mitosis, DNA, ploidy, yet his results shocked the world.
Multiple Choice Questions on Mendel Law of Segregation
Genotype vs Phenotype4:31
Mendel Laws; Part 2; Law of Independent Assortment28:18
Multiple Choice Questions on Law of Independent Assortment
Mendel Laws; Part 3; How to solve problems of Law of Segregation25:57
Apply the law of segregation to solve monohybrid crosses, using dominance and recessiveness to predict F1 and F2 phenotypes and genotypes for tall (T) versus dwarf (t) traits.
Mendel Laws; Part 4 Problems on Law of Segregation continued7:08
Determine parental genotypes from offspring phenotypes under Mendel's law of segregation, using crosses and dominant traits. Explore heterozygous and homozygous combinations and gamete formation to predict tall and dwarf offspring.
Mendel Laws, Part 5, Problems on Law of Independent Assortment31:00
Learn to solve two-trait dihybrid crosses under Mendel's law of independent assortment, using a rough black x smooth white mouse example to predict F1 and F2 phenotypes.
Dominance and Incomplete Dominance18:33
Explores dominance and incomplete dominance, defining genotype, phenotype, and alleles, and uses pea and snapdragon examples to show how heterozygotes create pink or intermediate phenotypes.
Co-Dominance12:49
Learn how codominance leads to two traits being equally expressed in the heterozygote, with roan coloration and AB blood group, and master predicting phenotypes via Punnett squares.
Quiz on Dominance, Incomplete Dominance and Co-Dominance
Test Cross; How to determine the unknown genotype15:05
Learn how the test cross reveals the unknown genotype by crossing a dominant phenotype with a homozygous recessive partner, using Punnett squares to distinguish homozygous and heterozygous states.
Multiple Choice Questions on Test Cross
Incomplete Penetrance15:18

Punnett Square; Part 123:05
The Punnett square is a square diagram that is used to predict the genotypes of a particular cross or breeding experiment. It is named after Reginald C. Punnett, who devised the approach in 1905. The Punnett square is a tabular summary of possible combinations of maternal alleles with paternal alleles
Punnett Square Part 227:33
Multiple Choice questions on Punnett Square
The Fork Line Method; Dihybrid crosses20:05
The Fork Line method is one the alternatives of the Punnett square and can be fun. Its has the same goals like the Punnett square but with a different style
The Fork Line Method; Trihybrid crosses21:00
Explore the fork-line method for tri-hybrid crosses to determine phenotype probabilities, avoiding a 64-box Punnett square. Learn three-trait inheritance for tall/dwarf, round/wrinkled, and yellow/green peas.
Multiple Choice Questions

Multiple Alleles; Part 1, An introduction24:11
Explore how multiple alleles shape phenotypes, with A, B, and O blood types as examples of codominance and incomplete dominance; understand three alleles, six genotypes, and four phenotypes.
Multiple Alleles; Part 227:41
Multiple Alleles; Blood Transfusion and Medical Condition15:47
Explore ABO multiple alleles and universal donor/recipient concepts in transfusion, and explain Rh factor dominance, sensitization, and pregnancy risks from maternal antibodies.

Chromosomal Sex Determination; the XX-XO System8:54
Examine sex determination using the xx xo system, where the presence or absence of a second x chromosome defines male or female offspring.
Chromosomal Sex Determination; the XX-XY System9:01
In the XX–XY system, females are homogametic XX and males are heterogametic XY; the sperm determines sex, and the SRY gene on Y initiates testes development.
Chromosomal Sex Determination; the ZZ-ZW System4:34
This lecture explains the zz-zw sex determination system used by birds. Females are heterogametic (z and w) and males are homogametic (zz), producing z- or w-bearing gametes, unlike xx-xy.
The male determining gene in Human; SRY Gene4:40
Temperature Dependent Sex Determination5:07
Positional/ Social Environmental Sex Determination4:06

Sex Linked Inheritance; X-linked Dominant Traits19:35
Explore X-linked dominant inheritance, where a single mutated X can affect males and females. Fathers pass X to daughters only; Alport syndrome illustrates hematuria and kidney involvement.
Sex linked inheritance, Part 2, X linked Recessive Traits16:56
Explain X-linked recessive inheritance, where males with a mutant X are affected and females are carriers unless they have two mutant Xs; hemophilia demonstrates carrier and affected offspring.

Requirements

Basic knowledge of Biology

Description

This course is designed for learners eager to master the fascinating world of Genetics. Dive into essential concepts that will shape your understanding of this dynamic field:

a. Discover Genetics: Explore its definition and historical milestones that have defined the discipline.

b. Groundbreaking Experiments: Uncover the classic studies that established DNA as the genetic material, including Thomas Hunt Morgan's pivotal work with Drosophila melanogaster and the groundbreaking discoveries of Griffith, Avery–MacLeod–McCarty, and Hershey-Chase.

c. Mendel's Legacy: Learn about the legendary Gregor Mendel and his foundational Laws of Segregation and Independent Assortment.

d. Genetic Traits: Understand the key concepts of dominance, recessive traits, incomplete dominance, and co-dominance.

e. DNA and RNA: Delve into the structures of DNA and RNA, exploring their differences and the significance of thymine in DNA versus uracil in RNA.

f. Genetic Predictions: Master Punnett Squares and the Fork Line Method for predicting genetic outcomes.

g. Multiple Alleles: Investigate the ABO blood types, their implications for blood transfusions, and related medical conditions.

h. Sex-Linked Traits: Gain insight into inheritance patterns, including X-linked dominant and recessive traits.

i. Understanding Mutations: Explore the various types of mutations—gene mutations, chromosomal mutations, silent mutations, missense mutations, and nonsense mutations.

Join us to unlock the secrets of Genetics and equip yourself with knowledge that will propel your studies and future career!

Who this course is for:

This course is for undergraduate/postgraduate biology students and faculty members

Fundamentals of Transmission Genetics/Classical Genetics

What you'll learn

Explore related topics

Course content

Introduction to the Course, History and Applications of Genetics4 lectures • 41min

Classical Experiments of Genetics4 lectures • 37min

The Structure and Function of Nucleic Acids (DNA and RNA)5 lectures • 1hr 4min

Understanding Mendel's Laws and Solving Genetic Problems10 lectures • 3hr 5min

Mastering Punnett Square and Forked Line Methods for Genetic Crosses4 lectures • 1hr 32min

Multiple Alleles and ABO Blood Grouping: Medical Importance for Fetal Health3 lectures • 1hr 8min

Sex Determination in Living Organisms6 lectures • 36min

Sex-Linked Inheritance: Dominant and Recessive Traits with Examples2 lectures • 37min

Introduction to Mutations: Types and Basic Concepts1 lecture • 21min

Requirements

Description

Who this course is for: