
The history of Epidemiology and Public Health, began with the adventures of John Snow in Victorian England. His investigation of a cholera outbreak in London led to the revelation that one can study disease with numbers and logic, and not just by looking at tissue samples and patient examinations.
Disease doesn't just appear magically one day in an otherwise healthy person. It takes time to develop, often first manifesting in childhood. In this lecture, we look at how disease develops through the lifespan, and what this means for how we detect, measure, and treat it.
In this section, students will learn about the fundamental designs of medical research projects, their advantages and disadvantages, and what they can and can't tell us.
Bias is the intellectual underpinnings of Epidemiology. Why are some statistics or study findings more believable than others?
Reliability and validity go hand in hand. But what are they? And why are they so important to medical research design and interpretation?
In Epidemiology, the word "experiment" means something very specific. The most well known example is the RCT, or randomized controlled (or clinical) trial. You can't understand medical research if you don't understand RCTs.
Epidemiologists are often described as experts in causal inference. But if you can't run an RCT, how do you really know that A causes B? In this lecture, we look at Bradford Hill's criteria for establishing causal relationships.
Surveillance has a "Big Brother" sound to it. But it's a hallmark of public health. Surveillance systems allow us to keep an eye out for spikes in disease incidence, and to motivate our limited resources accordingly.
Systematic reviews are considered the pinnacle of medical evidence. But what are they? How are they conducted? What are their strengths and weaknesses?
In the wake of the COVID pandemic, interest in the science of Epidemiology is soaring. But if you don't have a background in medical science, you probably have a skewed impression of what it's all about. Yes, there is a lot of math and statistics built into Epidemiology. After all, it is essentially the science of population health research without the ickiness of blood, ooze, or other fluids to deal with. Our major tools are logic, reason, and statistics!
However, the core concepts of Epidemiology are useful and relevant for everyone, not just researchers. It can help you read newspaper reports about research findings more fluently, for example. If you understand how the experts know what they claim to know, then you're halfway to being an expert yourself. I think it's a kind of super power. And as a result, I wish everyone could receive a minimal grounding in Epidemiology.
But because a lot of people are spooked by the prospect of mathematics, I've created this course specifically to avoid all computations and calculations. I have a follow-up course with that content included, for those who are interested. But for everyone else, these nine lectures are really all you need to get a solid footing in this science. I think it's ideal for journalists, math-phobic students, and any citizen interested in adding to their intellectual arsenal.
I hope you enjoy it!