
Conduct clinical research to collect data on events and populations, improve health management practices, test interventions including new drugs and vaccines, and deepen understanding of disease management.
Explores how clinical research tests interventions to improve standard care, involving patients or healthy volunteers, and follows strict protocols to assess cost, health care improvements, and impact on practice.
Butt Z A, Gilani AH, Nanan D, Sheikh AL, White F. Quality of pharmacies in Pakistan: a cross-sectional survey: Int J Qual Health Care 2005; 17(4): 307-313.
Creed-Kanashiro H, Ore B, Scurrah M, Gil A, Penny M. Conducting Research in Developing Countries: Experiences of the Informed Consent Process from Community Studies in Peru: J Nutr 2005; 135: 925–928.
Ferri CP, Schoenborn C, Kalra L, Acosta D, Guerra M, Huang Y, Jacob KS, Llibre Rodriguez JJ, Salas A, Sosa AL, Williams JD, Liu Z, Moriyama T, Valhuerdi A, Prince MJ. Prevalence of stroke and related burden among older people living in Latin America, India and China: J Neurol Neurosurg Psychiatry 2011; Epub ahead of print.
Hackshaw A. A Concise Guide to Clinical Trials 2009; Wiley-Blackwell, Chicester.
Learn how benefit versus risk affects volunteers in clinical research, including no potential benefits for participants, risks from questionnaires, genetic data, diagnostic tests, side effects, and possible placebo.
Laufer MK, van Oosterhout JJ, Perez MA, Kanyanganlika J, Taylor TE, Plowe CV, Graham SM. Observational cohort study of HIV-infected African children: Pediatr Infect Dis J 2006; 25(7): 623-7.
Minnies D, Hawkridge T, Hanekom W, Ehrlich R, London L, Hussey G. Evaluation of the quality of informed consent in a vaccine field trial in a developing country setting: BMC Med Ethic. 2008; 30(9): 15.
Mosby’s Medical Dictionary 8th ed. 2008. Mosby Publications.
Mystakidou K, Panagiotou I, Katsaragakis S, Tsilika E, Parpa E. Ethical and practical challenges in implementing informed consent in HIV/AIDS clinical trials in developing or resource-limited countries: SAHARA J 2009; 6(2): 46-57.
Explore case series as descriptive analyses based on case reports, similar to cross-sectional studies, used to analyze new diseases and multiple conditions without a control group.
Ochi N, Takigawa N, Yasugi M, Ishida E, Kawamoto H, Taniguchi A, Harada D, Hayashi E, Toda H, Yanai H, Tanimoto M, Kiura K. Obstructive jaundice at the initial presentation in small-cell lung cancer: International Medical Case Reports Journal 2010; 2010(3): 9-12.
Oh SS, Kim KS. Occupational asthma in Korea: J Korean Med Sci 2010; 25(Sup): S20-5.
Patil SB, Kale SM, Khare N, Math M, Jaiswal S, Jain A. Changing patterns in demography of cleft lip-cleft palate deformities in a developing country: the Smile Train effect-what lies ahead?: Plast Reconstr Surg 2011; 127(1): 327-32.
Phu PV, Hoan NV, Salvignol B, Treche S, Wieringa FT, Khan NC, Tuong PD, Berger J. Complementary foods fortified with micronutrients prevent iron deficiency and anemia in Vietnamese infants: J Nutr. 2010; 140(12): 2241-7.
Translate the protocol into a standard operating procedure (SOP) to achieve uniform task execution. Train staff and guard data integrity, participant safety, and compliant study procedures under GCP 1996 guidelines.
Preston-Martin S, Pogoda JM, Mueller B A, Lubin F, Modan B, Holly EA, Filippini G, Cordier S, Peris-Bonet R, Choi W, Little J, Arslan A. Results from an international case-control study of childhood brain tumors: the role of prenatal vitamin supplementation: Environ Health Perspect 1998; 106(Sup3): 887–892.
Tripathy P, Nair N, Barnett S, Mahapatra R, Borghi J, Rath S, Rath S, Gope R, Mahto D, Sinha R, Lakshminarayana R, Patel V, Pagel C, Prost A, Costello A. Effect of a participatory intervention with women’s groups on birth outcomes and maternal depression in Jharkhand and Orissa, India: a cluster-randomised controlled trial: Lancet 2010; 375: 1182–92.
Uner S, Cakir B, Yildirak K. Do we adequately respect the potential of routine primary health care services in reducing neonatal mortality in developing countries? The example of the Denizli cohort: Cah Sociol Demogr Med 2010; 50(4): 477-99.
Vandenbroucke JP. In Defense of Case Reports and Case Series: Ann Intern Med 2001; 134(4): 330-334.
Hello and Welcome to my Clinical Research Course!
I am certain that every professional, from a medical/nursing student to a physician, has or will encounter a research paper in their career; hence, I bring to you my course that lays out the fundamentals of clinical research.
I've arranged the entire course into four readily digestible modules, each with its own distinct title and some accompanying materials. All sections are summarised in the "Key concept" lectures, which serve as the final takeaways for the associated module. Every session concludes with a challenging quiz to ensure that you have understood the topic.
In the first section, we will define clinical research and compare it to standard care, as well as explain the value of clinical research’s impact on everyday life. The second section is followed by a researcher's ethical responsibilities, including the foundational principles of ethics to obtaining informed consent and the need for informed consent. The third section focuses on one of the most significant topics in this course, which is the many kinds of Study Designs and when to apply each. Following that, the course concludes with the SOPs that must be maintained when performing clinical research.
By the end of the course, you will be able to recognize and familiarise yourself with any Clinical research paper.