
Explore how plaque buildup from cholesterol and fatty deposits hardens arteries, causing arteriosclerosis and atherosclerosis, narrowing blood flow and risks of heart attack, stroke, peripheral artery disease, and kidney disease.
Explore the physiology of cholesterol, including the mevalonate pathway and HMG CoA reductase, statin targets, daily synthesis, and the role of phytosterols in intestinal reabsorption.
Cholesterol embolism arises when cholesterol from atherosclerotic plaque travels as an embolus to obstruct vessels. It causes skin symptoms, possible kidney failure, and is diagnosed by biopsy; statins help.
Explore natural strategies to lower cholesterol and boost HDL. Learn how the liver and lipoproteins transport cholesterol, including reverse cholesterol transport, and how dietary patterns shape LDL and HDL levels.
Focus on monounsaturated fats to lower harmful LDL and raise healthy HDL, while reducing cholesterol oxidation and supporting heart health through olive oil, nuts, and avocados.
Consider plant sterols and stanols, plant versions of cholesterol that compete with cholesterol absorption to lower LDL by 7.5–12% with 1.5–3 g daily, taken with a main meal.
Regulation of cholesterol synthesis relies on cholesterol sensing by SREBP1/2 with SCAP and INSIG in the ER, controlling LDL receptor and HMG-CoA reductase expression and degradation when cholesterol is high.
Explore how cholesterol travels in blood via lipoprotein complexes (vldl, idl, ldl, hdl) with amphipathic surfaces and apolipoproteins guiding receptor-driven tissue delivery.
Explore hypercholesterolemia, its lipid and lipoprotein patterns, and how diet, genetics, and disease influence ldl and hdl levels; learn dietary strategies to lower cholesterol and treatment options for severe cases.
Explore how long-standing high cholesterol can cause atherosclerosis, leading to ischemia, chest pain, stroke, and transient ischemic attacks, with visible signs like xanthomas and corneal deposits.
Identify how environmental and genetic factors drive hypercholesterolemia, including weight, diet, stress, loneliness, and medical conditions and medications. Explore how polygenic inheritance and APOB gene mutations influence cholesterol levels.
Diagnose hypercholesterolemia by interpreting cholesterol in mg/dl or mmol/L, assessing total, LDL, HDL, and non-HDL, triglycerides, and risks for coronary heart disease with direct LDL measurement when possible.
Explore how hypo cholesterol relates to membrane permeability and health outcomes. The lecture covers a U-shaped mortality curve and the role of statins and age in low cholesterol risk.
Explore organ meats as nutritious yet cholesterol-rich options, including chicken hearts with CoQ10, B12, iron, and zinc; note sardines as a nutrient-dense protein rich in vitamin D and B12.
Avoid fried foods like meat and cheese sticks due to cholesterol and trans fats that raise heart disease risk; limit processed foods, and cook at home to lower bad cholesterol.
Limit processed meats and sugary desserts to reduce cholesterol intake and lower risks of heart disease, colon cancer, obesity, and diabetes.
Explore peripheral vascular disease and how narrowed vessels reduce limb blood flow, causing pain and tissue damage. Learn how clots can cause pulmonary embolism and about 100,000 deaths in 2018.
There is no medicine that is greater than taking care of yourself and your lifestyle in terms of what you eat and how you eat. Blood cholesterol is a waxy, fat substance made by your liver. blood cholesterol is essential for good health. Your total body needs to perform important jobs, such as making hormones and digesting fatty food. Your body makes all the blood cholesterol it needs, which is why experts recommend that people eat as little dietary cholesterol as possible while on a healthy eating plan. Low- density lipoprotein ( LDL) or bad cholesterol. Having high level of LDL cholesterol can lead to plaque buildup in your arteries and result in heart disease or stroke. High- density lipoprotein (HDL) or good cholesterol. HDL is known as good cholesterol because high levels of it can lower your risk of heart disease and stroke.
Certain health conditions, such as type two diabetes and obesity, can raise your risk for high cholesterol. Lifestyle factors, such as eating a diet high in saturated fat and trans fats and not getting enough activity, can also raise your risk for high cholesterol. There are some people who have a family history of high cholesterol these group of people need to strategically take care of their cholesterol levels and adopt a better lifestyle. There are some high cholesterol warning signs that we need to be very careful about such as chest pain, dizziness and leg pain etc other low cholesterol warning signs also include depression and anxiety. It's always very important to know your cholesterol numbers because it help you to easily know what to do and when to do what you want to do. There are some foods that are very high in cholesterol such as fried foods, fast food, processed meats and desserts. These foods need to be avoided if possible, so you can be very healthy as adult. Let as remember that children can also have cholesterol, so parents need to take care of their children. Great exercises has a beneficial effect in keeping the body healthy and lowers cholesterol levels.