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Cardiac Anatomy & Physiology
Highest Rated
Rating: 4.6 out of 5(321 ratings)
2,701 students

Cardiac Anatomy & Physiology

Basic Medical Science
Created byMena Abdelsayed
Last updated 1/2019
English

What you'll learn

  • Understand the intricate mechanisms underlying cardiac excitation and contraction

Course content

1 section27 lectures3h 59m total length
  • Introduction - General Features of Adult Human Heart7:12

    Explore the heart’s general features: a muscular pump that delivers blood to all tissues, with about 70 ml stroke volume at 75 bpm, located in the mediastinum within the pericardium.

  • Cardiac External9:33
  • Cardiac Arteries10:28

    Examine the cardiac arteries and their branches, including the right and left coronary arteries, right marginal, posterior interventricular, left circumflex, diagonal, and left marginal branches, and coronary dominance.

  • Cardiac Veins5:01

    Explore the cardiac vasculature by tracing the coronary veins—the great cardiac vein, oblique vein, middle cardiac vein, interior cardiac vein, and the coronary sinus—from interventricular sulcus to the right atrium.

  • Cardiac Internal10:44

    Explore the heart anatomy: right atrium with vena cava openings, fossa ovalis and coronary sinus, tricuspid valve, right ventricle with papillary muscles, moderator and septal bands, and left heart valves.

  • Cardiac Valves8:14

    Explain the cardiac valves—the atrioventricular and semilunar valves—and their fibrous skeleton, cusps, and chordae, and how valve closure generates S1 and S2 heard across standard auscultation regions.

  • Cardiac Autonomic Innervation7:49
  • Cardiac Conduction System6:37

    Explore the cardiac conduction system, from the SA node and internodal pathways to the AV node, bundle of His, and Purkinje fibers, and understand delays that ensure ventricular filling.

  • Cardiac Muscle Histology10:06
  • Cardiac Gland & Hormones4:58
  • Cardiac Muscle Ultrastructure12:38

    Explore cardiac muscle ultrastructure, detailing the sarcomere with thick and thin filaments, titin, CapZ capping protein, troponin–tropomyosin regulation, and the calcium-release diad with t-tubules triggering contraction.

  • Cardiac Electrical Ionic Basis of Action Potential I12:44
  • Cardiac Electrical Ionic Basis of Action Potential II6:05
  • Cardiac Electrical Signal Generation in Pacemakers8:27
  • Cardiac Electrical Signal Generation in Muscle18:21
  • Cardiac Electrical Signal Propagation2:12

    Learn how cardiac electrical signals propagate to synchronize heart contractions, with intercalated disks and gap junctions enabling sodium and calcium currents between cells, described by Ohm's law.

  • Cardiac Excitation-Contraction Coupling8:25
  • Cardiac Contraction Mechanisms4:27
  • Cardiac Autonomic Control of Heart Rate11:38
  • Cardiac Autonomic Control of Heart Contraction12:29
  • Cardiac Electrocardiogram19:53
  • Cardiac Mean Electrical Axis2:19

    Determine the mean electrical axis from r-wave peaks across leads, or from the most isoelectric lead, using the circle of axes and perpendiculars.

  • Cardiac Cycle10:20

    Explore cardiac cycle from atrial systole to ventricular systole and diastole, highlighting right and left heart pressures across pulmonary and systemic circulations, valve closures, and ecg with s1 and s2.

  • Cardiac Metrics & Parameters6:10

    Cardiac output equals heart rate times stroke volume and ranges from 5 to 6 liters per minute. Preload, afterload, and contractility shape stroke volume and EDV/ESV balance.

  • Cardiac Force-Length Relationship9:33
  • Cardiac Force-Velocity Relationship5:21
  • Cardiac Pressure-Volume Relationship7:59

Requirements

  • Basic physiology and knowledge of sciences like chemistry, physics, and biology

Description

This is the most comprehensive course for cardiac anatomy & physiology. Graduate and undergraduate students in the health-care or life sciences fields will encounter a thorough overview of the anatomical features of the heart and the physiological mechanisms underlying a normal cardiac cycle. These mechanisms are covered in depth. Students will get an exhaustive tour of the heart: 1.)  external and internal anatomy of heart, 2.) coronary arteries and veins, 3.) cardiac conduction system, 4.) autonomic innervation of the heart and its role in regulating blood pressure, 5.) the heart as a gland or an endocrine organ and the hormones cardiac cells release, 6.) basic mechanisms of cardiac electrophysiology beginning with the cellular biophysics of ion channels all the way to action potentials in pacemaker and muscle cells of the heart, 7.) autonomic regulation of  chronotropy, inotropy, dromotropy, and contractility, 8.) basics of the ECG, including vector orientation and the mean electrical axis, 9.) and the effect of preload, afterload, and contractility on the force-length, force-velocity, and pressure-volume relationships in the heart. By the end of this course, students will develop a solid foundation in basic cardiology, enabling them to apply what they've learned to more advanced applications.

Who this course is for:

  • Students in biomedical sciences or medical students