
Explore the heart’s general features: a muscular pump that delivers blood to all tissues, with about 70 ml stroke volume at 75 bpm, located in the mediastinum within the pericardium.
Examine the cardiac arteries and their branches, including the right and left coronary arteries, right marginal, posterior interventricular, left circumflex, diagonal, and left marginal branches, and coronary dominance.
Explore the cardiac vasculature by tracing the coronary veins—the great cardiac vein, oblique vein, middle cardiac vein, interior cardiac vein, and the coronary sinus—from interventricular sulcus to the right atrium.
Explore the heart anatomy: right atrium with vena cava openings, fossa ovalis and coronary sinus, tricuspid valve, right ventricle with papillary muscles, moderator and septal bands, and left heart valves.
Explain the cardiac valves—the atrioventricular and semilunar valves—and their fibrous skeleton, cusps, and chordae, and how valve closure generates S1 and S2 heard across standard auscultation regions.
Explore the cardiac conduction system, from the SA node and internodal pathways to the AV node, bundle of His, and Purkinje fibers, and understand delays that ensure ventricular filling.
Explore cardiac muscle ultrastructure, detailing the sarcomere with thick and thin filaments, titin, CapZ capping protein, troponin–tropomyosin regulation, and the calcium-release diad with t-tubules triggering contraction.
Learn how cardiac electrical signals propagate to synchronize heart contractions, with intercalated disks and gap junctions enabling sodium and calcium currents between cells, described by Ohm's law.
Determine the mean electrical axis from r-wave peaks across leads, or from the most isoelectric lead, using the circle of axes and perpendiculars.
Explore cardiac cycle from atrial systole to ventricular systole and diastole, highlighting right and left heart pressures across pulmonary and systemic circulations, valve closures, and ecg with s1 and s2.
Cardiac output equals heart rate times stroke volume and ranges from 5 to 6 liters per minute. Preload, afterload, and contractility shape stroke volume and EDV/ESV balance.
This is the most comprehensive course for cardiac anatomy & physiology. Graduate and undergraduate students in the health-care or life sciences fields will encounter a thorough overview of the anatomical features of the heart and the physiological mechanisms underlying a normal cardiac cycle. These mechanisms are covered in depth. Students will get an exhaustive tour of the heart: 1.) external and internal anatomy of heart, 2.) coronary arteries and veins, 3.) cardiac conduction system, 4.) autonomic innervation of the heart and its role in regulating blood pressure, 5.) the heart as a gland or an endocrine organ and the hormones cardiac cells release, 6.) basic mechanisms of cardiac electrophysiology beginning with the cellular biophysics of ion channels all the way to action potentials in pacemaker and muscle cells of the heart, 7.) autonomic regulation of chronotropy, inotropy, dromotropy, and contractility, 8.) basics of the ECG, including vector orientation and the mean electrical axis, 9.) and the effect of preload, afterload, and contractility on the force-length, force-velocity, and pressure-volume relationships in the heart. By the end of this course, students will develop a solid foundation in basic cardiology, enabling them to apply what they've learned to more advanced applications.