
Explore covid-19 sequence databases and bioinformatics tools to study coronavirus biology, genome, and evolution; learn primer design, whole genome and next-generation sequencing analysis.
Discover the biology of SARS-CoV-2, including its spike protein and 30,000-base genome. Examine coronavirus taxonomy, animal-to-human transmission, and the emergence of variants and clades.
Discover NCBI's SARS-CoV-2 resources, including the first genome accession, full genome and protein sequences, gff/gfa files, and extensive data from sequencing platforms, PubMed, and clinical trials.
Learn to filter SARS-CoV-2 sequences on NCBI by genome completeness and geographic region, then download nucleotide data and build a phylogenetic tree to analyze relationships.
Explore the GISAID database, a rapid data-sharing platform for influenza and covid-19, offering genomic epidemiology tools and mutation analysis to support covid research.
Explore the UCSC SARS-CoV-2 genome browser to view the covid-19 genome, overlay datasets, and download immune cell and tissue data, plus Augustus gene predictions.
Explore the Cov3D database to analyze 3D structures of SARS-CoV-2 spike glycoprotein, RBD–ACE2 and antibody interactions, and peptide–MHC complexes for vaccine development and sequence diversity insights.
Explore the ARTIC network's protocols, lab-in-a-suitcase equipment, and software, including an epidemiology visualization tool, for real-time sampling, processing, and global spread visualization with genome sequencing and phylogenetic analysis.
Whole genome sequence assembled by Exatype for SRA sample SRR13767693
The covid-19 pandemic is of utmost concern. In almost a year and a half since the virus broke out in Wuhan, China, over 100,000 articles related to covid19 have been published in scientific journals because of the pandemic. In this course you can learn about practical bioinformatics tools which you can use in your own covid19 research. These include getting data from covid19 databases, live covid19 tracking software and sequence analysis tools such as whole genome assembly and variant calling. NGS tools are also discussed for covid research. Databases include resources on the National Center for Biotechnology Information Website and the GISAID database. Tools include Nextstrain and Nextclade as well as Exatype. This course is tailored towards students and researchers of all levels who are interested in studying coronavirus to help eradicate it. The tools shown during the course are fairly easy to use and do not presuppose too much prior knowledge of Windows or Linux. We will also cover primer design, because PCR (poly chain reaction) is a tool that is use in covid19 diagnosis. For this, we will learn how to use a tool called primer3 in Windows. This itself is a generally useful tool used in many other areas of research. Thanks for joining, and I do hope that you will greatly enjoy the course and learn new things to help win the battle against covid.