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Basics of Immunology
Rating: 4.4 out of 5(9 ratings)
27 students
Created bySinjini Bala
Last updated 12/2023
English

What you'll learn

  • Understand the basic concepts of innate and adaptive immunity and the mechanisms underlying immune responses to infections and vaccines.
  • Comprehend the structure and function of antibodies, T and B lymphocytes, and their role in immunological memory and autoimmune diseases.
  • Develop knowledge of immunodeficiencies, hypersensitivity reactions, transplantation immunology, and immunotherapy.
  • Gain insight into emerging areas in immunology such as the microbiome, aging, and cancer.

Course content

2 sections12 lectures34m total length
  • Introduction to Immunology2:29
    • Definition of immunology

    • Historical background

    • The importance of immunology

  • Innate Immunity2:40
    • Overview of innate immunity

    • Types of innate immunity (Physical barriers, Cellular barriers, Chemical barriers)

    • Innate immune receptors

    • Signaling pathways in innate immunity

  • Adaptive Immunity2:26
    • Overview of adaptive immunity

    • Types of adaptive immunity (Humoral immunity, Cell-mediated immunity)

    • Antigen recognition by T and B cells

    • Major histocompatibility complex (MHC)

  • Immunogens and Antigens2:15
    • Definition of immunogens and antigens

    • Types of immunogens and antigens

    • Factors influencing immunogenicity

    • Epitopes and antigenic determinants

  • Antibodies2:55
    • Overview of antibodies

    • Structure and classes of antibodies

    • Antibody functions

    • Antibody production

  • T-Lymphocytes2:27
    • Overview of T lymphocytes

    • Types of T lymphocytes (Helper T cells, Cytotoxic T cells, Regulatory T cells)

    • T cell receptor (TCR)

    • T cell activation and differentiation

  • B-Lymphocytes2:31
    • Overview of B lymphocytes

    • B cell receptor (BCR)

    • B cell activation and differentiation

    • Memory B cells

  • Complement System2:24
    • Overview of complement system

    • Complement components

    • Complement activation pathways

    • Complement functions

  • Major Histocompatibility Complex (MHC)3:07
    • Overview of MHC

    • Types of MHC molecules

    • MHC functions

    • MHC and antigen presentation

  • Immune Response to Infection3:16
    • Overview of immune response to infection

    • Immune response to bacteria, viruses, fungi, and parasites

    • Immunological memory

    • Vaccines

  • Immunotherapy3:21
    • Overview of immunotherapy

    • Types of immunotherapy (Cancer immunotherapy, Immune checkpoint inhibitors, Monoclonal antibodies)

    • Immunotherapy for infectious diseases and autoimmune diseases

  • Emerging Areas in Immunology4:40
    • Overview of emerging areas in immunology

    • Immunology and cancer

    • Immunology and aging

    • Immunology and the microbiome

    • Challenges and Future Directions

Requirements

  • This course is designed for undergraduate students with a basic knowledge of biology and biochemistry. It can also be used as a reference for graduate students and researchers in the field of immunology.

Description

The course "Basics of Immunology" is designed to provide learners with a comprehensive understanding of the basic principles and mechanisms of immunology. The course is ideal for undergraduate students studying biology, biomedical sciences, biochemistry, or related fields, graduate students and researchers in the field of immunology, and healthcare professionals seeking to gain knowledge of immunology for their practice.

The course begins by introducing learners to the innate and adaptive immune systems, immunogens and antigens, and the concept of immunological memory. Learners will then gain an understanding of the structure and function of antibodies, T and B lymphocytes, and the complement system. In subsequent chapters, the course covers the major histocompatibility complex (MHC), immune responses to infection, hypersensitivity, autoimmunity, immunodeficiencies, transplantation immunology, and immunotherapy.

The course is structured to provide a thorough understanding of each topic. Each chapter includes learning objectives, key terms, and case studies to reinforce the material covered. Learners will also have the opportunity to apply their knowledge through quizzes and assessments.

The course also covers emerging areas in immunology, such as the microbiome, aging, and cancer. Learners will gain insight into the role of the immune system in these areas and the potential applications of immunology in the treatment of these diseases.

Throughout the course, learners will develop critical thinking and problem-solving skills by analyzing case studies and applying their knowledge to real-world scenarios. Learners will also develop an appreciation for the interdisciplinary nature of immunology, including the integration of genetics, microbiology, and biochemistry.

Upon completion of this course, learners will have a solid foundation in immunology that will serve as a basis for further study in the field or for application in healthcare settings. They will be able to describe the mechanisms underlying immune responses and the role of the immune system in health and disease. Learners will also be able to identify the different components of the immune system and explain their roles in mediating immunity. Finally, learners will have an appreciation for the interdisciplinary nature of immunology and the potential applications of immunology in various fields, including medicine, biotechnology, and public health.

Who this course is for:

  • This course is intended for undergraduate students studying biology, biomedical sciences, biochemistry, or related fields who are interested in understanding the fundamentals of immunology. It is also suitable for graduate students and researchers in the field of immunology seeking a refresher or reference material. Healthcare professionals, such as physicians, nurses, and pharmacists, who need to understand the basic concepts of immunology in their practice may also find this course valuable.