Recombinant DNA technology- a game changer in cancer biology
- 1.5 hours on-demand video
- 4 articles
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- How different theories about cancer namely- chemical, chromosomal and viral, formed significant pieces of a puzzle that led to the emergence of two main concepts- Onocogenes and Tumor suppressors
- Students will focus on how tumor viruses revealed a bigger picture of cancer and also how identification of some of the viruses contributed significant tools to the field of recombinant DNA technology
- How cloning strategies accelerated the understanding of molecular dimension of carcinogenesis
- Students must be familiar with recombinant DNA tools and techniques and concepts of cloning
- Students must know basic concepts and terms in molecular biology such as DNA, mRNA, chromosomes, mitosis, meiosis etc.
This course focuses on historical theories and cloning strategies put forth to comprehend carcinogenesis. The objective is to travel back in time to the period when all the pieces of puzzle such as chemical carcinogens, retroviruses and chromosomal mutations came together to reveal the grand scheme of cancer and propose the underlying criteria for cancer development. The highlights of this lecture series are the experimental methods developed during 1960s to 1990s which built the foundation for the current model of cancer which stems from two concepts namely- oncogenes and tumor suppressor genes.
- High school students, college freshers and research students who are inquisitive enough to dig deeper into the powerful observations, brilliant experimental strategies and different theories about cancer that shaped the field of cancer biology we know today
- This course is not for absolute beginners who are looking for a typical in-depth college curriculum and not for experts in the field who are looking for advanced knowledge.
- This course would aid research students in tapping into the collective historical wisdom of the pioneers and use them as a guide in further advancing this field.