Acid-Base Disorders: From Basic to Advanced (Medical Course)

Name: Acid-Base Disorders: From Basic to Advanced (Medical Course)
Rating: 5.0 (3 reviews)

Build & revise your knowledge on Acid-Base disorders, essential when managing patients with acute medical conditions.

Created byChang Yin Chionh

Last updated 8/2021

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What you'll learn

Understand the Physiology and Principles of Acid-Base Homeostasis and Disorders
Able to evaluate the primary acid-base disturbance, respiratory or metabolic causes, using established principles and the anion gap
Able to identify mixed acid-base disorders
Able to determine a treatment and monitoring plan based on the underlying acid-base disorders
Apply the knowledge in daily clinical work

Course content

5 sections • 13 lectures • 1h 39m total length

Introduction - About me1:05
Chung-In, a practicing neurologist and nephrologist, introduces a series of teaching videos built from revision notes and case studies to help medical students grasp core concepts and improve patient care.
Physiology & Initial Evaluation9:06
Examine ammonia production in proximal tubule cells and bicarbonate reabsorption in proximal tubules, then apply Henderson-Hasselbalch-based rules to classify metabolic or respiratory acid-base disorders and their compensation.

Workup of High Anion Gap Metabolic Acidosis (HAGMA)8:55
Explains high anion gap metabolic acidosis and the anion gap concept, including unmeasured ions and albumin effects. Shows common causes such as lactic acidosis, ketoacidosis, uremia, and exogenous substances.
Workup of Normal Anion Gap Metabolic Acidosis7:31
Explore workup of normal anion gap metabolic acidosis, including the anion gap calculation, albumin influence, and urine anion gap and urine osmol gap to distinguish renal and gastrointestinal bicarbonate losses.

Part 1: Diagnosis and Types of Renal Tubular Acidosis5:47
Identify renal tubular acidosis types 1, 2, and 4, highlighting distal and proximal bicarbonate handling and using urine anion gap to distinguish renal from nonrenal loss.
Part 2: Differentiating Type 1 vs Type 2 RTA6:31
Differentiate type one and type two renal tubular acidosis using urine pH and bicarbonate loading tests, and interpret fractional excretion of bicarbonate to distinguish them.
Part 3: Overview of all RTAs and Treatment5:44
Differentiate renal tubular acidosis subtypes in normal anion gap acidosis using plasma potassium and urine pH. Assess underlying causes and treat with bicarbonate and potassium, watching for Fanconi syndrome.

Case Studies 01 - Basic8:06
Calculate the anion gap to distinguish high vs normal anion gap metabolic acidosis, link bicarbonate loss to diarrhea, and apply potassium pre-treatment with bicarbonate replacement.
Case Studies 02 - Intermediate Level Part I8:56
Calculate the anion gap and expected gap, adjusting for albumin, to distinguish delta gap from delta bicarbonate. Assess renal tubular acidosis type by potassium; replace bicarbonate.
Case Studies 02 - Intermediate Level Part II12:36
Assess concurrent hyperkalemia and normal anion gap metabolic acidosis as renal in origin. Use urine anion gap and bicarbonate loading tests to differentiate renal tubular acidosis types and guide therapy.
Case Studies 03 - Advanced Level Part I10:28
Analyze a high anion gap metabolic acidosis with concurrent metabolic alkalosis, using delta gap and delta bicarbonate to identify citrate toxicity, gastric losses, and kidney injury, informing management.
Case Studies 03 - Advanced Level Part II7:54
This case demonstrates a severe high anion gap metabolic acidosis with diabetic ketoacidosis and concomitant respiratory acidosis requiring mechanical ventilation and CRRT, highlighting delta gap analysis and rebound DKA considerations.

Requirements

Medical Students / Doctors who have completed Physiology modules
Basic knowledge in the primary functions of the kidney
Basic knowledge in clinical acid-base disorders

Description

This is a medical course on Acid-Base Disorders for medical students, trainees and medical practitioners. It is a progressive course for which starts from basic principles, moving stepwise to intermediate and advanced level knowledge. Doctors caring for patients who are ill or at risk of deterioration must be able to detect and manage acid-base disorders on the go. The course materials are intended to be highly relevant to clinical work, especially for those working in an acute care setting.

Presented in easy & digestible bits, the concepts are reinforced to improve learning and retention. Lots of visual aids, including the use of the Gamblegram, helps to simplify the topic which can sometimes be overwhelming.

The course includes:

Revision of the basics:
Respiratory acid-base disorders
High Anion Gap Metabolic Acidosis (HAGMA)
Normal Anion Gap Metabolic Acidosis (NAGMA)
Interpretation of the serum Anion Gap
Interpretation of the Urine Anion Gap & Urine Osmolar Gap
Complex and Mixed acid-base disorders
Differentiating Type 1, 2 & 4 Renal Tubular Acidosis (the Bicarbonate Loading Test)
Treatment of acid-base disorders

After a series of concise lectures, real-life clinical case studies for practice are available at graded levels of difficulty. The learner can apply the knowledge and try solving the clinical problems. Answers & rationale behind the answers are also provided.

This course is suitable at all levels, such as Medical Students, Nephrology & Internal Medicine & Critical Care Trainees and Practicing Physicians revising for Board Recertification.

Who this course is for:

Medical Students
Residents, Senior Residents / Fellows in Nephrology, Internal Medicine, Critical Care, Anaesthesiology
Practicing Physicians in Nephrology, Internal Medicine, Critical Care, Anaesthesiology
Senior Doctors due for Board Review examinations
Specialist Trainees (all medical fields or surgical fields which require critical care knowledge)

Acid-Base Disorders: From Basic to Advanced (Medical Course)

What you'll learn

Explore related topics

Course content

Introduction & Basics2 lectures • 10min

High Anion Gap Metabolic Acidosis & Normal Anion Gap Metabolic Acidosis2 lectures • 16min

Mixed Disorders1 lecture • 7min

Renal Tubular Acidosis3 lectures • 18min

Case Studies5 lectures • 48min

Requirements

Description

Who this course is for: